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| Section 1. How to choose
which one to use |
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For
non-aqueous samples or those containing a high organic concentration,
use PTFE. It is unaffected
by most organic solvents, concentrated acids and bases, propellants
and cryogenic fluids. It can also be used for the sterilisation
of gases and air, alcohols, cleaning acids, alkalis and organic
solvents. |
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For
most aqueous samples use Cellulose Acetate. It has low protein binding and is ideal for filtering
biological samples, and the sterilisation or clarification of
aqueous solutions. |
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For
high protein binding use Nylon.
It is fine for the filtration of organic and aqueous solutions
over the pH range 3-10, and is recommended for pharmaceutical
sterilisation. |
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An
alternative for aqueous samples is PVDF, but do not use with more than 60% organic solvent.
It has low non-specific protein binding. |
| For optimum filtration
or sterilisations use 0.2u filters. Where viscosity is higher,
or the particle concentration makes filtration too slow, use
0.45u. |
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